City of Hope Reveals Its Bold Vision to Invest More Than $1B for World-Class Cancer Care at FivePoint Gateway in Orange County

Tuesday, June 25, 2019

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City of Hope, a world-renowned independent research and treatment center for cancer, today revealed plans to invest more than $1 billion to develop and support a new comprehensive cancer campus at FivePoint Gateway in Orange County, accelerating highly specialized cancer care, phase I-III clinical trials, and precision medicine and early detection to the nation’s sixth most populous county. This unprecedented initiative in Orange County is part of City of Hope’s commitment to speeding pioneering treatments and scientific breakthroughs to the people who need them today.

“City of Hope is dramatically expanding to provide a cancer network of unparalleled scale for this community; It will be a nexus of service, science, and care,” said Robert Stone, president and CEO, City of Hope. “It is made possible by our partnership with FivePoint Holdings and a strong community of philanthropic supporters in Orange County and beyond, who stand shoulder to shoulder with us in our determination to eradicate cancer.”

Last year, City of Hope and FivePoint announced their partnership to build a $200 million, 73,000-square-foot cancer center in FivePoint’s Great Park Neighborhoods by 2025. As planning progressed, FivePoint and City of Hope expanded their vision for the Great Park as a model community of the future with easily accessible world-class health and wellness as a core offering. In line with this vision, City of Hope significantly increased its investment with a focus on highly specialized cancer care, research, and lifesaving treatments.

Now a space as big as the vision, the cancer campus on approximately 11 acres of land at FivePoint Gateway in Irvine will include an approximately 190,000-square-foot building that will be a center of innovative cancer research and treatments. This increased investment cuts City of Hope’s time to build the new campus by half, with the center expected to open its doors in 2021.

City of Hope officials cite several reasons for an expanded presence in the region.  Nearly 20 percent of residents leave the area for advanced care, with many heading to City of Hope’s main campus in Duarte, California – an up to two-hour commute away. In addition, despite its reputation for healthy living, Orange County is not immune from the one-in-three national statistic for cancer incidence. In fact, the cancer incidence rate in the county is projected to increase by 18 percent over the next decade. Cancer risk increases with age and the county’s population is aging faster than the U.S. average.

City of Hope is answering the call to extend its personalized care, outstanding research and lifesaving treatments closer to home with the same sense of urgency as its scientists who find and deliver cures. The City of Hope cancer campus is planned to include:

  • Orange County’s only specialty hospital dedicated solely to treating and curing cancer.
  • An outpatient cancer center offering diagnostic imaging and screenings, precision medicine and early detection, medical oncology, chemotherapy, radiation therapy, surgical oncology, and ambulatory surgery.
  • A clinical research center offering phase I-III clinical trials.
  • Personalized supportive care services that include palliative care physicians, psychiatrists, social workers and others who partner with patients and their families to address the many physical and emotional issues that can arise during and after treatment. City of Hope is the model for other institutions across the country.
  • Access to a wide range of solid tumor and blood cancer specialists dedicated to finding the best treatments for each patient.   

This campus will be an extension of City of Hope in Duarte, providing access to highly specialized cancer experts and treatment for the most complex cases, such as bone marrow transplants, stem cell transplants, and CAR T cell therapy.

City of Hope Orange County will include additional clinical locations that will provide medical oncology and infusion services, ensuring easy access to care throughout the region. As previously announced, City of Hope is planning to open its Newport Beach facility later this year, providing residents with a more convenient way to receive leading-edge medicine.

For updates on the initiative, or to become a volunteer or philanthropic partner of City of Hope Orange County, go to

Category: Partner News, Community News